Irregular periods, stubborn weight changes, acne, unwanted hair growth, or low energy can leave you wondering what is happening with your body. Polyendocrine Metabolic Ovarian Syndrome (PMOS), formerly known as Polycystic Ovary Syndrome (PCOS), is a hormonal, metabolic, and reproductive condition that can affect your menstrual cycle, skin, hair, fertility, weight, and overall wellness. Instead of focusing on one symptom at a time, personalized services can help identify the interconnected factors contributing to your symptoms and build a more complete plan for feeling better.
At Your Formula, Dr. Jonathan Zaidan, MD, and Suzana Marku, NP-C, provide personalized, evidence-based PMOS/PCOS care through a clinician-led model. With telehealth services available to eligible patients throughout Michigan and Florida, Your Formula combines comprehensive evaluation, laboratory review when appropriate, individualized treatment, and ongoing support.
What Is PMOS (Formerly PCOS)?
Polyendocrine Metabolic Ovarian Syndrome (PMOS) is the new name for the condition historically known as Polycystic Ovary Syndrome (PCOS). The updated name better reflects that this is a complex endocrine and metabolic condition rather than simply a problem involving ovarian “cysts.”
PMOS can involve irregular or absent ovulation, increased androgen activity, and metabolic changes such as insulin resistance. It can affect reproductive health, weight, skin and hair, energy, and long-term metabolic wellness.
PMOS does not look the same for everyone. One person may struggle primarily with irregular periods, while another notices acne, weight changes, unwanted facial hair, thinning scalp hair, or difficulty conceiving.
Common Signs and Symptoms of PMOS/PCOS
Symptoms may develop gradually and can vary throughout different stages of life. Common concerns include:
- Irregular or missed menstrual periods
- Difficulty with regular ovulation
- Acne or oily skin
- Unwanted facial or body hair
- Thinning scalp hair
- Weight gain or difficulty managing weight
- Low energy
- Blood sugar or metabolic concerns
- Mood changes
- Fertility concerns
Higher androgen activity can contribute to symptoms such as acne and excess hair growth, while ovulatory dysfunction may cause irregular or absent periods.
Treating the “Why” Behind PMOS
Your Formula takes a broader approach to PMOS by looking at factors that may be contributing to your symptoms rather than treating every patient with the same protocol. The program considers several interconnected areas of hormonal, metabolic, reproductive, and overall health.
Insulin Resistance
Insulin resistance occurs when the body does not respond to insulin as effectively as it should. It is common in PMOS and can influence blood sugar regulation, hunger, weight, energy, and hormone activity.
Addressing metabolic health can therefore be an important part of PMOS management for some patients. When weight and metabolic concerns are significant, medical weight loss can also be considered as part of a broader individualized care plan.
Hormonal Imbalance and Androgen Excess
PMOS can disrupt normal hormone patterns and contribute to irregular periods, acne, mood changes, unwanted hair growth, or scalp hair thinning.
Higher androgen levels are a characteristic feature of many cases of PMOS and can contribute to reproductive concerns as well as acne, unwanted hair growth, or scalp hair thinning. Personalized skin and hair care can address these concerns when they are part of the broader clinical picture.
Chronic Inflammation
Inflammation can be one part of the broader metabolic picture in PMOS. Your Formula considers inflammation alongside hormones, nutrition, metabolic health, and other wellness factors when developing an individualized plan.
Elevated Cortisol and Stress
Chronic stress can influence sleep, energy, appetite, mood, and everyday wellness. Your Formula considers stress and lifestyle factors because they can make existing PMOS symptoms more difficult to manage.
Support can include strategies related to sleep, stress management, nutrition, activity, and other sustainable lifestyle habits.
Metabolic Dysfunction
PMOS is more than a reproductive condition. It can also involve changes in insulin sensitivity, glucose regulation, weight, and other aspects of metabolic health. People with PMOS can have an increased risk of developing metabolic conditions such as type 2 diabetes.
Your Formula can evaluate these factors when weight changes, cravings, low energy, or other metabolic concerns are part of your symptoms.
Ovulatory Dysfunction
PMOS can interfere with regular ovulation, leading to unpredictable cycles or missed periods. Ovulatory changes can affect reproductive health and contribute to fertility challenges for some patients.
Understanding your menstrual patterns and broader hormonal health can help your provider determine which treatment strategies are appropriate.
Personalized PMOS/PCOS Treatment Options
There is no single treatment that is right for everyone with PMOS. Your plan depends on your symptoms, laboratory findings when appropriate, health history, reproductive goals, and metabolic needs.
Treatment through Your Formula can include:
- Natural bioidentical hormone therapy
- Natural birth control
- Peptide therapy
- Nutrition and lifestyle guidance with our fitness coach, with or without weight loss medications
- Reduction in androgens
- Metabolic health support
- Support for skin and hair concerns
- Cycle management
- Stress and sleep support
- Ongoing clinical monitoring
Your Formula tailors treatment based on clinical assessment, patient goals, and response to care rather than using a single standard PMOS/PCOS protocol.
Why Choose Your Formula for PMOS Care
Personalized PMOS care should recognize that this condition involves far more than the ovaries. Your Formula provides individualized, medically guided care that considers hormonal, metabolic, reproductive, and overall wellness factors while recognizing that every patient’s symptoms and priorities are different.
Each patient begins with a detailed intake, laboratory review when appropriate, and provider evaluation. If treatment is indicated, your plan can include prescriptions, supplementation, nutrition and lifestyle support, metabolic care, and continued follow-up based on your progress.
Your Formula works with a PCAB-approved pharmacy and is LegitScript certified, supporting a care experience centered on clinical oversight and individualized attention.
Frequently Asked Questions
Does a previous PCOS diagnosis still apply now that the name has changed?
Yes. PMOS is the updated name for the same condition, so an existing PCOS diagnosis remains valid. The change recognizes its broader hormonal and metabolic effects. You may still see PCOS in medical records, educational resources, and insurance paperwork while terminology transitions. Your care should remain focused on your individual needs.
Can you have PMOS without ovarian cysts?
Yes. You do not need ovarian cysts to have PMOS. In adults, diagnosis considers ovulatory dysfunction, signs of increased androgen activity, and ovarian findings after excluding other causes. Ultrasound is not always necessary when irregular cycles and androgen excess are already present. Diagnostic requirements differ for adolescents, so age matters during evaluation.
Can PMOS affect you at a healthy weight?
Yes. PMOS can occur across body sizes, and metabolic concerns are not limited to people with overweight or obesity. Your provider may recommend blood sugar assessment and other screening based on the condition and your history. Care can address cycle changes, skin symptoms, nutrition, and long-term health without making weight loss your primary goal.
Does PMOS mean you cannot get pregnant?
No. PMOS can make conception more difficult when ovulation is irregular, but it does not mean pregnancy is impossible. Some people conceive without fertility treatment; others need additional support. Tell your provider if you want to become pregnant, because your goals affect medication choices. Specialist fertility evaluation may be appropriate depending on your circumstances.
Should you seek care if you rarely have periods?
Yes. Infrequent or absent periods deserve evaluation, even if they seem convenient. Pregnancy, thyroid conditions, and other concerns can also cause missed periods. With PMOS, prolonged gaps between periods can increase the risk of an overly thick uterine lining. Your provider can discuss appropriate cycle management and whether further evaluation is needed.
Is there a specific diet that works best for PMOS?
No single diet has been shown to be best for everyone with PMOS. A sustainable eating pattern should reflect your preferences, nutritional needs, and health goals. Nutrition guidance can help you build practical habits without unnecessary restriction. Physical activity and other lifestyle changes can support health even when they do not produce weight loss.
How quickly will you notice improvements with treatment?
Timing depends on your symptoms, treatment, and how you respond. Cycle patterns, acne, unwanted hair growth, and metabolic measures may improve at different rates. Follow-up helps your provider assess progress and side effects rather than relying on one deadline. Don't change your prescribed treatment on your own if results take longer than expected.
Can your PMOS care begin through telehealth?
Eligible individuals in Michigan and Florida can begin with a Your Formula consultation. Suzana Marku, NP-C, reviews your symptoms, history, and goals, with laboratory testing when appropriate. Telehealth can support evaluation and follow-up, although examinations, imaging, or specialist care may require local visits. Bring previous test results and a current medication list to your consultation.
Begin Your PMOS Care
Initial Visit With a Prescribing Provider
$125
Your first visit includes a detailed review of your symptoms, health history, medications, wellness goals, and relevant thyroid concerns.
Prescribing Provider Follow-Up
$75
Meet with your prescribing provider to review laboratory results, discuss progress, and make treatment adjustments when clinically appropriate.
Registered Nurse Follow-Up
$50
Receive additional support, guidance, and follow-up care from a registered nurse as you continue your treatment plan.
Complimentary Wellness Session
Your first conversation is on us.
15 minutes, one-on-one, with founder Suzana Marku, NP-C. Your symptoms, your goals, and an honest read on whether Your Formula is right for you. No cost. No obligation.
Take Control of Your Health With PMOS Care
PMOS can affect multiple areas of health, from menstrual cycles and fertility to metabolism, energy, skin, hair, and emotional well-being. A personalized approach can help you better understand how these factors connect and identify treatment strategies that fit your individual needs.
Your Formula provides personalized PMOS care with telehealth services available to eligible patients throughout Michigan and Florida. Call (313) 380-5779 to book a consultation and begin building a clinician-guided treatment plan around your symptoms, metabolic health, hormonal wellness, and goals.
